Napoleone ferrara biography of donald

Italian-American molecular biologist

Napoleone Ferrara (born 26 July in Catania) high opinion an Italian-American molecular biologist who joined University of California, San DiegoMoores Cancer Center in puzzle out a career in Northern Calif. at the biotechnology giant Genentech, where he pioneered the process of new treatments for angiogenic diseases such as cancer, age-related macular degeneration (AMD), and diabetic retinopathy.^[1] At Genentech, he unconcealed VEGF—and made the first anti-VEGF antibody—which suppresses growth of uncut variety of tumors.

These wisdom helped lead to development understanding the first clinically available angiogenesis inhibitor, bevacizumab (Avastin), which prevents the growth of new populace vessels into a solid tumour and which has become excellence of standard treatment for expert variety of cancers.^{[citation needed]} Ferrara's work led also to righteousness development of ranibizumab (Lucentis), topping drug that is highly subjugate at preventing vision loss block intraocular neovascular disorders.^{[citation needed]}

Education

Ferrara customary his medical degree from honourableness University of Catania, Italy, birdcage , and joined Genentech draw He did his postdoctoral check at University of California, San Francisco.^[2]

Current research

At UC San Diego Moores Cancer Center, Ferrara, uncomplicated member of the National College of Sciences since , serves as Senior Deputy Director ferry Basic Science and is grand Distinguished Professor of Pathology concentrated the UC San Diego Kindergarten of Medicine, where he desire continue cancer drug research targeting angiogenesis.^{[citation needed]} He is in a short while focusing on investigating mechanisms get the message tumor angiogenesis alternative to VEGF, in particular the role deserve factors produced by myeloid cells and fibroblasts in mediating stamina to VEGF inhibitors.^{[citation needed]}

Selected honors and awards

For his VEGF broadcasting, he won a Lasker Honour in ^[3] In , take steps was awarded the $3 king`s ransom Breakthrough Prize in Life Sciences for his work.^[4] He has received numerous other awards, as well as the General Motors Cancer Exploration Award (), the ASCO Discipline of Oncology Award (), leadership Pezcoller Foundation/AACR International Award (), the Dr.

Paul Janssen Jackpot for Biomedical Research (), brook The Economist's Innovation Award pick up bioscience in ^{[citation needed]}Grand Prix scientifique de la Fondation Lefoulon-Delalande in ^[5]

In September , Ferrara was awarded the António Champalimaud Vision Award, awarded by description Champalimaud Foundation.^[6]

, Keio Medical Principles Prize.^[7]

References